Journal article
Quantifying low birth weight, preterm birth and small-for- Gestational-age effects of malaria in pregnancy: A population cohort study
MJ Rijken, AM De Livera, SJ Lee, ME Boel, S Rungwilailaekhiri, J Wiladphaingern, MK Paw, M Pimanpanarak, S Pukrittayakamee, JA Simpson, F Nosten, R McGready
Plos One | Published : 2014
Abstract
Background: The association between malaria during pregnancy and low birth weight (LBW) is well described. This manuscript aims to quantify the relative contribution of malaria to small-for-gestational-age (SGA) infants and preterm birth (PTB) in pregnancies accurately dated by ultrasound on the Thai-Myanmar border at the Shoklo Malaria Research Unit. Methods and Findings: From 2001 to 2010 in a population cohort of prospectively followed pregnancies, we analyzed all singleton newborns who were live born, normal, weighed in the first hour of life and with a gestational age (GA) between 28+0 and 41+6 weeks. Fractional polynomial regression was used to determine the mean birthweight and standa..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
The Shoklo Malaria Research Unit is part of the Mahidol Oxford University Research Unit, at the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand and supported by the Wellcome Trust of Great Britain. MJR and MEB were supported by the Christophe Merieux Prize to FN (2008). AL was supported by the National Health & Medical Research Centre of Australia (NHMRC) Centre of Research Excellence 1035261, awarded to the Victorian Centre for Biostatistics (ViCBiostat). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.